The CRISPR-Cas System

It’s about time I covered CRISPR, don’t you think? It’s the hottest topic in science since space-tardigrades! Once again, no, water bears can’t live in space naked, they have to be in a dry tun. Back to CRISPR though, this new gene editing technology isn’t actually new at all. Bacteria have been using it as an adaptive immune system to remember past viral infections. Some History and Terminology CRISPR stands for Clustered Regularly Interspaced Short Palindromic Repeats. They are exactly what their name says they are… In 1987, scientists noticed these repeating sequences in E. Coli and eventually, other scientists…

Nanoparticles

Tiny UPS… or something You’ve learned about phage therapy, quorum sensing and quorum quenching, which means, hello PhD! I’m just kidding, no grad student has the time to jump from topic to topic like this. But for us curious nerds, the next topic in the fight against antibiotic resistant bacteria is nanoparticles. Specifically, using them to deliver drugs. Sometimes, antibiotics don’t reach the cell because of the biofilm, and this physical problem requires a physical solution: tiny delivery systems. Nanoparticles Nanoparticles are usually some sort of metal or carbon polymer. They have a positive charge so that they can interact…